Sildenafilis the first-line treatment for pulmonary arterial hypertension that works by dilating the arterial vessels. It helps improve blood flow through the lungs and the heart. Sildenafil also improves penile erection by blocking PDE5, an enzyme in the walls of blood vessels that affects blood flow and supports cells signal in the body. It is a type5 inhibitor of the phosphodiesterase family that works as a vasodilating drug and is currently recommended by the WHO for group 1 patients. The drug is marketed as Revatio® and is rapidly replacing the non-selective vasodilators which have been in use for several years now.
How does Sildenafil work?
Sildenafil works by relaxing and widening the blood vessels in the lungs to increase easy blood flow. It reduces constriction as blood moves through the vessels and into other important organs such as the heart. While constricted blood flow would cause the delay in oxygenated blood supply reaching some areas of the body, this drug reverses all this, which helps the body to perform its important functions normally. For instance, when pulmonary arterial hypertension is effectively controlled, it allows the heart and the lungs to work better and enhances exercise ability. Since you can breathe more effortlessly, you can take a jog through the tracks without overloading your heart.
To use this drug, a doctor will need to have enough information about the patient, including the family history. This drug should be taken while strictly following the doctor’s instructions. It should be taken orally three times a day in three equal doses for the period indicated by the doctor. It would be best if you never used more than the prescribed dose as it can lead to other serious side effects. The dosage should be based on your medical history, the disease’s progress, and your response to treatment. Before you start on this drug, ensure to tell your doctor of any other medications you are currently taking since some drugs may counter-react and cause more harm.
Be sure not to increase the dosage or take the drug more often than is prescribed by your doctor, as this may alter the gains you are getting from the drug. By taking heed to the prescription, you are likely to improve your lung health and reduce pulmonary arterial hypertension. If you take this medication without mixing it with other drugs, you will reap the most benefits from it. Be sure to keep your doctor informed on your progress, and if your condition worsens, he will know what to do to reverse it. It is important to understand that pulmonary hypertension has no known cure. Sildenafil only helps reduce its effects and spread, although if you observe your doctor’s directions, the condition can eventually be corrected. But that will depend on its progression and the steps taken in controlling it. Sticking to the dosage and healthy living can contribute to improved blood flow and a healthily working heart. Sildenafil is doubtlessly the best option for improved blood circulation and for fighting pulmonary arterial hypertension.